That is actually the title of a book I read a few years ago. And here I am, faced with the decision of what brand name to choose for my FSH: Gonal-F, Follistim or Bravelle.
Anyway, Bravelle is a simple method: There's the solvent, there's the powder, you mix them together and you inject them. Straightforward and familiar. Although if I need large doses, I will end up mixing the contents of several vials. Sounds cumbersome, but the volume to be injected stays the same at all times.
Then there's the Gonal-f, which according to their website is preferred by two out of three patients. It also says that "The Gonal-f® RFF Pen has a visual confirmation scale that lets you know the precise dose you set is ready to inject, reducing the chance of dosing errors." If I am reading it correctly, several doses are provided in one Pen. I prefer throwing away syringes after using them. Also, If I am mixing the doses myself, I don't think I have to worry about dosing errors. Still, there must be a reason why people prefer this method.
Pen. As the cartridge empties, you may be left with an incomplete dose and need two injections for one dose. Not a big deal. Can this happen with Gonal-f too? I see less potential for mistake with this type of pen compared to the Gonal-f pen, where there's the potential to pull the plunger and then realize that you have entered the wrong dose.
Well, there they are, my three choices. I am inclined to choose the Bravelle, simply because I like the name and the injection method is familiar. Follistim could also be injected with regular syringes, but larger doses probably mean larger volumes. Plus, refrigeration is a must with Follistim and Gonal-f. Not that I should worry about that, but I did grow up in a third world country where power outages were not that rare.
What would you choose? If you have used any of these drugs, do you have any comments to share?